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A multimodal submillimeter MRI atlas of the human cerebellum
Nature
We introduce a multifaceted cerebellar atlas based on high-resolution multimodal MRI, facilitating the understanding of the neurodevelopment and...
قبل 10 أشهر
Cervical and thoracic spinal cord gray matter atrophy is associated with disability in patients with amyotrophic lateral sclerosis
Wiley Online Library
Background and purpose In amyotrophic lateral sclerosis (ALS), there is an unmet need for more precise patient characterization through quantitative,...
قبل 10 أشهر
Multi-view fusion of diffusion MRI microstructural models: a preterm birth study
Frontiers
Objective: High Angular Resolution Diffusion Imaging (HARDI) models have emerged as a valuable tool for investigating microstructure with a higher degree of...
قبل شهر واحد
Evidence of association between higher cardiorespiratory fitness and higher cerebral myelination in aging
PNAS
Emerging evidence suggests that altered myelination is an important pathophysiologic correlate of several neurodegenerative diseases, including Alzheimer...
قبل 5 أشهر
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis
Nature
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and progressive neurodegeneration.
قبل شهرين (2)
Fig. 1 Ex vivo analysis of presymptomatic spinal cord of ALS mice by...
ResearchGate
Our previous MRI diffusion tensor imaging studies detected early white matter changes in the spinal cords of mice carrying the G93A-SOD1 mutation.
قبل 77 شهرًا
Intersectional strategy to study cortical inhibitory parvalbumin-expressing interneurons
Nature
The Vgat-Cre/PV-Flp/tdTomato mouse line seems to be a more reliable animal model for functional studies of GABAergic PV interneurons.
قبل 11 شهرًا
SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study
BioMed Central
Sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitors may have additional beneficial metabolic effects on circulating metabolites beyond glucose...
قبل 8 أشهر
Quantitative MRI at 7-Tesla reveals novel frontocortical myeloarchitecture anomalies in major depressive disorder
Nature
We uniquely combined Ultra-High Field MRI at 7.0 Tesla with Quantitative Imaging to map intracortical myelin (proxied by longitudinal relaxation time T 1 ) and...
قبل 7 أشهر
Multiparametric MRI dataset for susceptibility-based radiomic feature extraction and analysis | Scientific Data
Nature
Multiple sclerosis (MS) is a progressive demyelinating disease impacting the central nervous system. Conventional Magnetic Resonance Imaging (MRI)...
قبل 7 أشهر